METHOD OF OBTAINING N-(2-BENZHYDRYLETHYL)-N-(1-PHENYLETHYL)-AMINE RACEMATE, ITS OPTICALLY ACTIVE ANTIPODES OR THEIR SALTS

A process for the preparation of the compound of the formula I and its salts is described. It is based on the reduction of the acid amide of the formula II. The reduction is advantageously carried out using a complex metal hydride. The compound of the formula I forms racemates, the synthesis claimed...

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Bibliographic Details
Main Authors DEZHE KORBONITSH,HU, PAL KISHSH,HU, KALMAN KHARSHANI,HU, ENRE PALOSHI,HU
Format Patent
LanguageEnglish
Published 15.04.1978
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A process for the preparation of the compound of the formula I and its salts is described. It is based on the reduction of the acid amide of the formula II. The reduction is advantageously carried out using a complex metal hydride. The compound of the formula I forms racemates, the synthesis claimed leading to the optically active components. Under the name phendilin, the final substance is used pharmaceutically against angina pectoris.
Bibliography:Application Number: SU19752174852