STRAIN STREPTONUCES LAVENDOFOLIAL 12/3A PRODUCER OF ALKACYNOMYCINS A AND B

The antibiotics aclacinomycin A and B which have anticancer activity, and mixtures thereof, are obtained by cultivation of the strain 12/3-A of Streptomyces lavendofoliae under aerobic conditions in a nutrient medium which contains carbon- and nitrogen-containing compounds at a temperature of 20 - 3...

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Main Authors IVANITSKAYA L.P.,SU, KRYUCHKOVA E.I.,SU, VESELOVA S.I.,SU, NAVASHIN S.M.,SU, ESIPOV S.E.,SU, CHERNYSHOV A.I.,SU, KLYUEV N.A.,SU, FOMINA I.P.,SU, TAJG M.M.,SU, EGOROV L.V.,SU, TERENTEVA T.G.,SU, SOJFER V.S.,SU, SINGAL E.M.,SU, OSTANINA L.N.,SU
Format Patent
LanguageEnglish
Published 23.11.1984
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES USING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The antibiotics aclacinomycin A and B which have anticancer activity, and mixtures thereof, are obtained by cultivation of the strain 12/3-A of Streptomyces lavendofoliae under aerobic conditions in a nutrient medium which contains carbon- and nitrogen-containing compounds at a temperature of 20 - 30 DEG C and at a pH of 6 - 8.5 for 48 - 96 h.
Bibliography:Application Number: SU19823459347