Derivati di pirazina quali bloccanti di ENaC

Compounds of Formula I: and pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 have the meanings as indicated in the specification, are useful for treating diseases mediated by blockade of the epithelial sodium channel. Pharmaceutical composit...

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Bibliographic Details
Main Authors SMITH NICHOLA, EDWARDS LEE, HUNT PETER, BHALAY GURDIP, HOWSHAM CATHERINE
Format Patent
LanguageItalian
Published 09.07.2015
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Summary:Compounds of Formula I: and pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 have the meanings as indicated in the specification, are useful for treating diseases mediated by blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Bibliography:Application Number: SM20150000133T