Sali di addizione di ammine contenenti gruppi idrossilici e/o carbossilici con deriviati dell'acido amminonicotinico come inibitori di dhodh

The present invention is directed to novel water-soluble pharmaceutically acceptable, crystalline addition salts of (i) an amine containing one or more hydroxyl and/or carboxylic groups with (ii) amino nicotinic acid derivatives of formula (I) wherein R a , R b , R c and R d independently represent...

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Main Authors CARRERA CARRERA FRANCESC, GRACIA MARTIN DIGNA JOSE, BOIX BERNARDINI MARIA CARMEN, PEREZ GARCIA JUAN BAUSTISTA
Format Patent
LanguageItalian
Published 08.11.2013
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Summary:The present invention is directed to novel water-soluble pharmaceutically acceptable, crystalline addition salts of (i) an amine containing one or more hydroxyl and/or carboxylic groups with (ii) amino nicotinic acid derivatives of formula (I) wherein R a , R b , R c and R d independently represent groups selected from hydrogen atoms, halogen atoms, C 1-4 alkyl groups which may be optionally substituted by 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups, and C 1-4 alkoxy groups which may be optionally substituted by 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups, and pharmaceutically acceptable solvates thereof.
Bibliography:Application Number: SM20130000104T