2-SACCHARINYLMETHYL AND 4,5,6,7-TETRAHYDRO-2-SACCHARINYL- -METHYL PHOSPHATES, PHOSPHONATES AND THEIR USING

Novel 4-R1-R2-R3-2-saccharinylmethyl, 4-R4-4-R5-6-R6-4,5,6,7-tetrahydro-2-saccharinylmethyl and 4,7-C-4,5,6,7-tetrahydro-2-saccharinylmethyl phosphates, phosphonates and phosphinates of formulas I, II and IIA respectively are useful in the treatment of degenerative diseases, and compositions contain...

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Bibliographic Details
Main Authors DESAI RANJIT C, COURT JOHN J, HLASTA DENNIS J, SUBRAMANYAM CHAKRAPANI
Format Patent
LanguageEnglish
Published 10.05.1995
Edition6
Subjects
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Summary:Novel 4-R1-R2-R3-2-saccharinylmethyl, 4-R4-4-R5-6-R6-4,5,6,7-tetrahydro-2-saccharinylmethyl and 4,7-C-4,5,6,7-tetrahydro-2-saccharinylmethyl phosphates, phosphonates and phosphinates of formulas I, II and IIA respectively are useful in the treatment of degenerative diseases, and compositions containing them, methods for using them to treat degenerative diseases, and processes for their preparation by reaction of the corresponding 2-halomethylsaccharins with a phosphate, phosphonate or phosphinic acidderivative.
Bibliography:Application Number: SK19920003716