B form of the potassium salt of (S)- omeprazole, pharmaceutical composition and use thereof

It is disclosed the B form of 5-methoxy-2-[[(4-methoxy-3,5- dimethyl-2-pyridinyl) methyl] sulfinyl]-1H-benzimidazole, known under the generic name omeprazole, particularly crystalline form of the potassium salt of the (S)-enantiomer of 5-methoxy-2-[[(4- methoxy-3,5-dimethyl-2-pyridinyl) methyl] sulf...

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Bibliographic Details
Main Author NILSSON MATHS
Format Patent
LanguageEnglish
Slovak
Published 03.05.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:It is disclosed the B form of 5-methoxy-2-[[(4-methoxy-3,5- dimethyl-2-pyridinyl) methyl] sulfinyl]-1H-benzimidazole, known under the generic name omeprazole, particularly crystalline form of the potassium salt of the (S)-enantiomer of 5-methoxy-2-[[(4- methoxy-3,5-dimethyl-2-pyridinyl) methyl] sulfinyl]-H- benzimidazole. Also, the process for preparing such a form of the potassium salt of (S)-omeprazole and pharmaceutical compositions containing it are disclosed. Opísaná je forma B 5-metoxy-2-[[(4-metoxy-3,5-dimetyl-2- pyridinyl)metyl]sulfinyl]-1H-benzimidazolu, ktorý je známy pod triviálnym názvom omeprazol, najmä kryštalická forma draselnej soli (S)-enantioméru 5-metoxy-2-[[(4-metoxy-3,5-dimetyl-2- pyridinyl)metyl]sulfinyl]-1H-benzimidazolu. Opísaný je ajspôsob prípravy takejto formy draselnej soli (S)-omeprazolu a farmaceutické kompozície, ktoré ju obsahujú.
Bibliography:Application Number: SK20010001037