Peroral aqueous solution comprising as active ingredient 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4- piperidinyl]-7-benzofuran-carboxamide and method for its preparation

A peroral aqueous solution having a pH ranging from 2 to 5 and comprising as active ingredient 4-amino-5-chloro-2,3- dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofuran- carboxamide or a pharmaceutically acceptable acid addition salt thereof and further benzoic acid. A method for its preparat...

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Bibliographic Details
Main Author DE PROOST EDDY ANDRE JOSEE
Format Patent
LanguageEnglish
Slovak
Published 05.01.2006
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A peroral aqueous solution having a pH ranging from 2 to 5 and comprising as active ingredient 4-amino-5-chloro-2,3- dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofuran- carboxamide or a pharmaceutically acceptable acid addition salt thereof and further benzoic acid. A method for its preparation, which comprises including benzoic acid in such solution and adjusting the pH range from 2 to 5. Perorálny vodný roztok, ktorý má pH v rozpätí od 2 do 5 a obsahuje ako aktívnu zložku 4-amino-5-chlór-2,3-dihydro-N-[1- (3-metoxypropyl)-4-piperidyl]-7-benzo-furánkarboxamid alebo jeho farmaceuticky prijateľnú adičnú soľ a ďalej kyselinu benzoovú. Spôsob jeho prípravy, ktorý zahŕňa začlenenie kyseliny benzoovej do takého roztoku a úpravu pH do rozpätia od 2 do 5.
Bibliography:Application Number: SK20010001519