Process of purification of cyclosporin A
Object of the invention is a process for the chromatographic preparation of cyclosporin A from a crude product containing cyclosporin complex by using a column filled with silica gel and by the application of multistep chromatography with a column filled with normal phase silica gel and by a solvent...
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Main Authors | , , , , |
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Format | Patent |
Language | English Slovak |
Published |
04.11.2003
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Edition | 7 |
Online Access | Get full text |
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Summary: | Object of the invention is a process for the chromatographic preparation of cyclosporin A from a crude product containing cyclosporin complex by using a column filled with silica gel and by the application of multistep chromatography with a column filled with normal phase silica gel and by a solvent mixture containing toluene as the major component.
Postup chromatografického čistenia cyklosporínu A zo surového produktu, obsahujúceho cyklosporínovú zmes, s použitím kolóny naplnenej silikagélom a aplikáciou viacstupňovej chromatografickej metódy na kolóne plnenej normálnou silikagélovou fázou, v zmesi rozpúšťadiel obsahujúcej ako hlavnú zložku toluén. ŕ |
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Bibliography: | Application Number: SK19980001618 |