USE OF ISOXAZOLE-4-CARBOXAMIDES AND HYDROXYALKYLIDENE-CYANOACETAMIDES FOR PREPARING DRUGS

There is disclosed the use of isoxazole-4-carboxamides of the general formula (I) and their hydrolytic products, hydroxyalkylidenecyanoacetamides of the general formula (Ia) and (Ib) whereof substituents R1, R2, R3, R7 and R8 have their meanings given in the Description; their stereoisomeric forms a...

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Bibliographic Details
Main Authors BARTLETT ROBERT R, KAMMERER FRIEDRICH-JOHANNES
Format Patent
LanguageEnglish
Slovak
Published 12.02.2001
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:There is disclosed the use of isoxazole-4-carboxamides of the general formula (I) and their hydrolytic products, hydroxyalkylidenecyanoacetamides of the general formula (Ia) and (Ib) whereof substituents R1, R2, R3, R7 and R8 have their meanings given in the Description; their stereoisomeric forms and/or physiologically tolerable salts for the preparation of drugs suitable for treating cancer diseases. Je opísané použitie izoxazol-4-karboxamidov všeobecného vzorca (I) a ich hydrolytických produktov, amidov hydroxyalkylidénkyánoctovej kyseliny všeobecného vzorca (Ia) a (Ib), v ktorých substituenti R1, R2, R3, R7 a R8 majú významy uvedené v opise, ich stereoizomérnych foriem a/alebo ich fyziologicky znášanlivých solí, na výrobu liekov na liečenie rakovinových ochorení.ŕ
Bibliography:Application Number: SK19980001376