ACID ANHYDRIDES AND PREPARATION AND USE THEREOF

Anhydrides of general formula (I), wherein Ar is an aryl radical, and either R1 is C6H5-CO or (CH3)3C-O-CO, R2 is a hydrogen atom and R3 is a hydroxy function protective grouping, or R1 is (CH3)3C-O-CO and R2 and R3 together form a saturated 5 or 6-membered heterocyclic ring; preparation thereof; an...

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Bibliographic Details
Main Author MAS JEAN-MANUEL
Format Patent
LanguageEnglish
Slovak
Published 08.11.1999
Edition6
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Anhydrides of general formula (I), wherein Ar is an aryl radical, and either R1 is C6H5-CO or (CH3)3C-O-CO, R2 is a hydrogen atom and R3 is a hydroxy function protective grouping, or R1 is (CH3)3C-O-CO and R2 and R3 together form a saturated 5 or 6-membered heterocyclic ring; preparation thereof; and uses thereof for preparing taxane derivatives having general formula (III), wherein R = H, acetyl; R1 is C6H5-CO or (CH3)3C-O-CO, and having antitumoral properties.
Bibliography:Application Number: SK19940000929