A PROCESS FOR THE PREPARATION AND/OR PURIFICATION OF CLAVULANE ACID AND ITS SALT

The procedure of preparation and/or purification closed to clavulane acid or a salt of that which acceptable for pharmaceutical point of view is provided based on the contact of tertiary octylamine with non-purified clavulane acid or with an unsteady derivative of it, while an organic solvent is pre...

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Bibliographic Details
Main Authors COOK MICHAEL A, WILKINS ROBERT B
Format Patent
LanguageEnglish
Published 06.08.1997
Edition6
Subjects
APPARATUS THEREFOR
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:The procedure of preparation and/or purification closed to clavulane acid or a salt of that which acceptable for pharmaceutical point of view is provided based on the contact of tertiary octylamine with non-purified clavulane acid or with an unsteady derivative of it, while an organic solvent is present, and after that the created tertiary octylamine salt closed to clavulane acid is isolated, in the next stage the created salt is converted to the clavulane acid or to the salt or ester of that which is acceptable form pharmaceutical point of view.
Bibliography:Application Number: SK19940001532