CYCLIC AZAPEPTIDES WITH ANGIOGENIC EFFECT

Compounds of the formula Iin which aArg, aGly, aAsp, aX and aY have the meanings indicated in claim 1,and their salts,can be used as integrin inhibitors, in particular for the prophylaxis and treatment of diseases of the circulation, in thrombosis, cardiac infarct, coronary heart diseases, arteriosc...

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Bibliographic Details
Main Authors KESSLER HORST, JONCZYK ALFRED, SCHMITT JORG, GOODMAN SIMON, WERMUTH JOCHEN
Format Patent
LanguageEnglish
Published 12.06.2000
Edition7
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds of the formula Iin which aArg, aGly, aAsp, aX and aY have the meanings indicated in claim 1,and their salts,can be used as integrin inhibitors, in particular for the prophylaxis and treatment of diseases of the circulation, in thrombosis, cardiac infarct, coronary heart diseases, arteriosclerosis, in pathological processes which are supported or propagated by angiogenesis and in tumour therapy.
Bibliography:Application Number: SK19990001735