METHOD FOR PREPARING STREPTOGRAMINES

PCT No. PCT/FR96/00575 Sec. 371 Date Oct. 16, 1997 Sec. 102(e) Date Oct. 16, 1997 PCT Filed Apr. 16, 1996 PCT Pub. No. WO96/33213 PCT Pub. Date Oct. 24, 1996A method for preparing streptogramins of the formula (I): (I) wherein R1 is methyl or ethyl, R2 is H and X and Y together form an oxo radical,...

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Main Authors MUTTI STEPHANE, GRONDARD LUC, BARRIERE JEAN-CLAUDE, LEFEVRE PATRICK
Format Patent
LanguageEnglish
Published 04.02.1998
Edition6
Subjects
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Summary:PCT No. PCT/FR96/00575 Sec. 371 Date Oct. 16, 1997 Sec. 102(e) Date Oct. 16, 1997 PCT Filed Apr. 16, 1996 PCT Pub. No. WO96/33213 PCT Pub. Date Oct. 24, 1996A method for preparing streptogramins of the formula (I): (I) wherein R1 is methyl or ethyl, R2 is H and X and Y together form an oxo radical, or R1 is ethyl, R2 and X are H and Y is H or OH, or else R1 is ethyl, R2 is OH and X and Y together form an oxo radical, by demethylation of a synergistin derivative of the formula (II): efined above, by means of a treatment with a periodate in an acetic medium, followed by a treatment in an aqueous medium.
Bibliography:Application Number: SK19970001404