ISOQUINOLIN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF

• Main Authors: EASTMAN Brian Walter, MITTAPALLI Gopi Kumar, MAK Chi Ching, KC Sunil Kumar, CHIRUTA Chandramouli, CAO Jianguo, BOLLU Venkataiah
• Format: Patent
• Language: English; Slovenian
• Published: 31.08.2021
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Isoquinoline compounds of formula I for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns an isoquinoline compound thereof, for use in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal...