ISOQUINOLIN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF
Isoquinoline compounds of formula I for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns an isoquinoline compound thereof, for use in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal...
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Main Authors | , , , , , , |
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Format | Patent |
Language | English Slovenian |
Published |
31.08.2021
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Subjects | |
Online Access | Get full text |
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Summary: | Isoquinoline compounds of formula I for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns an isoquinoline compound thereof, for use in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states. |
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Bibliography: | Application Number: SI20170030725T |