COMBINATION THERAPY FOR TREATING MALIGNANCIES

Provided are methods and compositions for treating cancers in patients carrying an IDH1 mutation using a combination of an inhibitor of a mutant IDH1 enzyme and a DNA demethylating agent.

Saved in:
Bibliographic Details
Main Authors KNIGHT Robert Douglas, VISWANADHAN Krishnan, DIMARTINO Jorge, AGRESTA Samuel V, KENVIN Laurie, CHOPRA Vivek Saroj Kumar, MACBETH Kyle J, XU Qiang
Format Patent
LanguageEnglish
Slovenian
Published 29.04.2022
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
Online AccessGet full text

Cover

More Information
Summary:Provided are methods and compositions for treating cancers in patients carrying an IDH1 mutation using a combination of an inhibitor of a mutant IDH1 enzyme and a DNA demethylating agent.
Bibliography:Application Number: SI20160031384T