CRYSTALLINE FORMS OF 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRIMIDINE-5-CARBOXAMIDE

The invention provides a method of preparing compound of formula (iv),by contacting the compound of formula (iii) with R1NH2 in the presence of a base or a Lewis acid, in a solvent as defined herewith. The invention further provides a compound of formula (iii),and tautomers thereof, wherein R2 is su...

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Bibliographic Details
Main Authors KOTHARE Mohit Atul, HUANG Lianfeng, HILGRAF Robert, XU Jean, LI Ying, ZOU Daozhong, ZOU Nanfei, FERRETTI Antonio Christian, BEAUCHAMPS Marie Georges, NAGY Mark A, YONG Kelvin Hin-yeong, BOERSEN Nathan Andrew, MUSLEHIDDINOGLU Jale, MAN Hon-Wah
Format Patent
LanguageEnglish
Slovenian
Published 30.10.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The invention provides a method of preparing compound of formula (iv),by contacting the compound of formula (iii) with R1NH2 in the presence of a base or a Lewis acid, in a solvent as defined herewith. The invention further provides a compound of formula (iii),and tautomers thereof, wherein R2 is substituted or unsubstituted C1-8 alkyl, or substituted saturated cycloalkyl as defined herein.
Bibliography:Application Number: SI20150031322T