SPLICEOSTATIN ANALOGS

The present invention is directed to novel cytotoxic spliceostatin analogs and derivatives, to antibody drug conjugates thereof, and to methods for using the same to treat medical conditions including cancer.

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Bibliographic Details
Main Authors PUTHENVEETIL Sujiet, RATNAYAKE Anokha Sayani, HE Min, GREEN Michael Eric, DIRICO Kenneth John, YANG Hui Yu, TESKE Jesse Alexander, SUBRAMANYAM Chakrapani, O'DONNELL Christopher John, KOEHN Frank Erich, EUSTAQUIO Alessandra S, HE Haiyin
Format Patent
LanguageEnglish
Slovenian
Published 30.04.2018
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention is directed to novel cytotoxic spliceostatin analogs and derivatives, to antibody drug conjugates thereof, and to methods for using the same to treat medical conditions including cancer.
Bibliography:Application Number: SI20130030950T