BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY

The invention relates to bicyclic heterocycle compounds of formula (I):or tautomeric or stereochemically isomeric forms, N-oxides, pharmaceutically acceptable salts or the solvates thereof; wherein R1, R2a, R2b, R3a, R3b, R5, R6, R7, R8, R9, p and E are as defined herein; to pharmaceutical compositi...

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Main Authors CHESSARI Gianni, GRIFFITHS-JONES Charlotte Mary, TAMANINI Emiliano, DAY James Edward Harvey, BUCK Ildiko Maria, JOHNSON Christopher Norbert, CHIARPARIN Elisabetta, WOOLFORD Alison Jo-Anne, FREDERICKSON Martyn, HEIGHTMAN Thomas Daniel, HOWARD Steven
Format Patent
LanguageEnglish
Slovenian
Published 30.07.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The invention relates to bicyclic heterocycle compounds of formula (I):or tautomeric or stereochemically isomeric forms, N-oxides, pharmaceutically acceptable salts or the solvates thereof; wherein R1, R2a, R2b, R3a, R3b, R5, R6, R7, R8, R9, p and E are as defined herein; to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
Bibliography:Application Number: SI20120031896T