Self-assembling structures composed of one polypeptide chain with at least three segments which are able form coiled helices

• Main Authors: BOZIC SABINA, DEBELJAK NIKA, MIKLAVIC SPELA, POHAR JELKA, BREMSAK ROBERT, BENCINA MOJCA, JERALA ROMAN, VERCE MARKO, LUKAN ANJA, FEKONJA OTA, DOLES TIBOR, FRIEDERICH JOZEFA, GRADISAR HELENA, JELERCIC URSKA, HAFNER BRATKOVIC IVA
• Format: Patent
• Language: English; Slovenian
• Published: 29.04.2011
• Subjects: CHEMISTRY; MANUFACTURE OR TREATMENT THEREOF; METALLURGY; NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS,MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES ASDISCRETE UNITS; NANOTECHNOLOGY; ORGANIC CHEMISTRY; PEPTIDES; PERFORMING OPERATIONS; TRANSPORTING

The invention describes a preparation of self-assembling nanostructures and a process for preparation of self-assembling nanostructures from polypeptides which are composed of at least three segments forming a coiled helix, which are assembling themselves into one sole polypeptide chain in a defined sequence which enables the composing into defined nano-cages or nano-nets. Nanostructures can be assembled from one sole polypeptide chain, yet which is composed of three, four or six segments forming coiled helices and are stacked into nano-cages, nano-nets or nano- tubes. Izum opisuje pripravo samosestavljivih nanostruktur in proces za pripravo samosestavljivih nanostruktur iz polipeptidov, ki so sestavljeni iz vsaj treh segmentov, ki tvorijo ovito vijačnico, ki se povezujejo v eno samo polipeptidno verigo v definiranem zaporedju, ki omogoča sestavljanje v definirane nano-kletke ali nano-mreže. Nano-strukture se lahko sestavljajo iz ene same polipeptidne verige, ki pa je sestavljena iz treh, štirih ali šestih segmentov, ki tvorijo ovite vijačnice in se zlagajo v nano-kletke, nano-mreže ali nano-cevke.