Process for the preparation of the mesylate salt trihydrate of 1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol and intermediates useful therefor
The present invention is directed to a novel process for the preparation of the mesylate trihydrate of the compound of formula (I), (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-pro panol: The present invention is further directed to a process for the preparation of a (2S)-(+)-c...
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| Main Authors | , , |
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| Format | Patent |
| Language | English Slovenian |
| Published |
28.02.2005
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| Edition | 7 |
| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention is directed to a novel process for the preparation of the mesylate trihydrate of the compound of formula (I), (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-pro panol: The present invention is further directed to a process for the preparation of a (2S)-(+)-compound of formula (II): wherein R is a protecting group. In addition, the present invention relates to intermediates useful in said processes. |
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| AbstractList | The present invention is directed to a novel process for the preparation of the mesylate trihydrate of the compound of formula (I), (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-pro panol: The present invention is further directed to a process for the preparation of a (2S)-(+)-compound of formula (II): wherein R is a protecting group. In addition, the present invention relates to intermediates useful in said processes. |
| Author | RAINVILLE JOSEPH PHILIP SINAY TERRY GENE JR WALINSKY STANLEY WALTER |
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| DocumentTitleAlternate | Postopek priprave trihidrata mesilatne soli 1-(4-hidroksifenil)-2-(4-hidroksi-4-fenilpiperidin-1-il)-1-propanola in za to primerni intermediati |
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| RelatedCompanies | PFIZER PRODUCTS INC |
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| Snippet | The present invention is directed to a novel process for the preparation of the mesylate trihydrate of the compound of formula (I),... |
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| SubjectTerms | APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| Title | Process for the preparation of the mesylate salt trihydrate of 1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol and intermediates useful therefor |
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