INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES

The invention relates to compounds of general formula I wherein R is heteroaryl optionally substituted by R7; or R is heterocycloalkyl or heterocycloalkenyl, optionally substituted by R8; or R is X wherein X is -NR11R12; and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use -...

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Main Authors VEDSOE, PER, MAANSSON, KRISTOFFER, LIANG, XIFU, HOEGBERG, THOMAS, VIFIAN, THOMAS, GRUE-SOERENSEN, GUNNAR
Format Patent
LanguageEnglish
Published 31.07.2013
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Summary:The invention relates to compounds of general formula I wherein R is heteroaryl optionally substituted by R7; or R is heterocycloalkyl or heterocycloalkenyl, optionally substituted by R8; or R is X wherein X is -NR11R12; and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use -alone or in combination with one or more other pharmaceutically active compounds- in therapy, for preventing, treating or ameliorating diseases or conditions responsive to stimulation of neutrophil oxidative burst, responsive to stimulation of keratinocyte IL-8 release or responsive to induction of necrosis.
Bibliography:Application Number: SG20130046438