HIGH AFFINITY HUMAN ANTIBODIES TO HUMAN PROTEASE-ACTIVATED RECEPTOR-2

The present invention provides antibodies that bind to protease-activated receptor-2 (PAR-2) and methods of using same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human PAR-2. The antibodies of the invention are useful, inter alia, for t...

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Main Authors LACCROIX-FRALISH, MICHAEL, L, PAPADOPULOS, NICHOLAS, J, MACDONALD, LYNN, MURPHY, ANDREW, J, SALZLER, ROBERT, R, MORRA, MARC, R
Format Patent
LanguageEnglish
Published 27.04.2012
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Summary:The present invention provides antibodies that bind to protease-activated receptor-2 (PAR-2) and methods of using same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human PAR-2. The antibodies of the invention are useful, inter alia, for the treatment of diseases and disorders associated with one or more PAR- 2 biological activities, including the treatment of pain conditions, inflammatory conditions and gastrointestinal conditions.
Bibliography:Application Number: SG20120015228