DR6 ANTIBODIES INHIBITING THE BINDING OF DR6 TO APP, AND USES THEREOF IN TREATING NEUROLOGICAL DISORDERS

Methods and compositions comprising DR6 antagonists for use in treating neurological disorders, including Alzheimer's disease, are provided. The DR6 antagonists include anti-APP antibodies, anti-DR6 antibodies, DR6immunoadhesins and DR6 variants (and fusion proteins thereof) which enhance growt...

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Bibliographic Details
Main Authors NIKOLAEV, ANATOLY, TESSIER-LAVIGNE, MARC
Format Patent
LanguageEnglish
Published 28.02.2012
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Methods and compositions comprising DR6 antagonists for use in treating neurological disorders, including Alzheimer's disease, are provided. The DR6 antagonists include anti-APP antibodies, anti-DR6 antibodies, DR6immunoadhesins and DR6 variants (and fusion proteins thereof) which enhance growth, regeneration or survival of mammalian neuronal cells or tissue. No suitable figure
Bibliography:Application Number: SG20110096492