PROCESS FOR THE MANUFACTURE OF ORGANIC COMPOUNDS
A method for preparing an alkali metal salt comprising: (a) condensing a disilyloxydiene with an aldehyde in the presence of a titanium (IV) catalyst in an inert solvent to form a 5(S)-hydroxy-3-ketoester; (b) reducing the 5(S)-hydroxy-3-ketoester to a 3(R),5(S)-dihydroxyester in the presence of a d...
Saved in:
Main Authors | , , , , , |
---|---|
Format | Patent |
Language | English |
Published |
29.06.2010
|
Edition | 7 |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | A method for preparing an alkali metal salt comprising: (a) condensing a disilyloxydiene with an aldehyde in the presence of a titanium (IV) catalyst in an inert solvent to form a 5(S)-hydroxy-3-ketoester; (b) reducing the 5(S)-hydroxy-3-ketoester to a 3(R),5(S)-dihydroxyester in the presence of a di(lower alkyl)methoxyborane; and (c) hydrolyzing the 3(R), 5(S)- dihydroxyester in the presence of an aqueous base to form an alkali metal salt. No Figure to accompany abstract |
---|---|
Bibliography: | Application Number: SG20060050942 |