THERAPEUTIC AGENT FOR CARTILAGE DISORDER
The inventors of the present invention searched for a substance that is effective in treating a cartilage disorder, and as a result, found that, in an animal model of joint cartilage deficiency, an HMGB1 fragment peptide having a specific amino acid sequence exhibits the effect of reproducing a heal...
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Main Authors | , , , , |
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Format | Patent |
Language | English |
Published |
28.05.2021
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Subjects | |
Online Access | Get full text |
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Summary: | The inventors of the present invention searched for a substance that is effective in treating a cartilage disorder, and as a result, found that, in an animal model of joint cartilage deficiency, an HMGB1 fragment peptide having a specific amino acid sequence exhibits the effect of reproducing a healthy cartilage tissue including a hyaline cartilage. Based on this finding, the present invention provides a pharmaceutical composition that contains the specific HMGB1 fragment peptide and that is for preventing and/or treating a cartilage disorder. |
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Bibliography: | Application Number: SG20211104015Y |