METHODS, APPARATUS, AND COMPUTER-READABLE MEDIA FOR GLYCOPEPTIDE IDENTIFICATION

A method identifies glycopeptides in a sample. The method includes converting a mass spectrum of MS1 precursors of the sample into a plurality of nodes in a graph, each node corresponding to one mass and one retention time of a glycopeptide to be identified in the sample; calculating differences in...

Full description

Saved in:
Bibliographic Details
Main Authors NGUYEN-KHUONG, Terry, RUDD, Pauline Mary, CHOO, Sern Farh Matthew
Format Patent
LanguageEnglish
Published 29.07.2020
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
Online AccessGet full text

Cover

More Information
Summary:A method identifies glycopeptides in a sample. The method includes converting a mass spectrum of MS1 precursors of the sample into a plurality of nodes in a graph, each node corresponding to one mass and one retention time of a glycopeptide to be identified in the sample; calculating differences in the mass and/or retention time between all combinations of pairs of the nodes; generating a graph theoretic network of the nodes; and predicting compositions of the glycopeptides in the sample based on the graph theoretic network of the nodes so as to identify the glycopeptides.
Bibliography:Application Number: SG20201105497X