MPGES-1 INHIBITOR FOR THE TREATMENT OF OSTEOARTHRITIS PAIN

The present invention relates to a microsomal prostaglandin E synthases-1 ("mPGES-1") inhibitor for the treatment of osteoarthritis pain in a subject. For example, the present invention relates to a method of treating moderate osteoarthritis pain in a subject in need thereof by orally admi...

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Bibliographic Details
Main Authors SANT, Sumit, GUDI, Girish, MENON, Vinu C A, TANDON, Monika, KHAIRATKAR-JOSHI, Neelima, TALLURI, Ravi
Format Patent
LanguageEnglish
Published 29.04.2020
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to a microsomal prostaglandin E synthases-1 ("mPGES-1") inhibitor for the treatment of osteoarthritis pain in a subject. For example, the present invention relates to a method of treating moderate osteoarthritis pain in a subject in need thereof by orally administering to the subject a substituted triazolone compound as a mPGES-1 inhibitor. The present invention also relates to pharmaceutical compositions comprising the mPGES-1 inhibitor, and to processes for preparing such pharmaceutical compositions.
Bibliography:Application Number: SG20201102307T