SOLID PHARMACEUTICAL COMPOSITIONS FOR TREATING HCV

The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutic...

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Main Authors NARIS, Marius, KYEREMATENG, Samuel, GARRETT, Colleen, LANDER, Ute, HACH, Harald, GAO, Yi, JAYASANKAR, Adivaraha, STEITZ, Benedikt, ASMUS, Katharina, OBERMILLER, Constanze, SIMON, Michael, MUELLER, Thomas, WESTEDT, Ulrich, SCHNEIDER, Katrin, SEVER, Nancy, REUL, Regina, ZHU, Donghua, TONG, Ping
Format Patent
LanguageEnglish
Published 28.05.2020
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Summary:The present invention features solid pharmaceutical compositions comprising Compound 1 and Compound 2. In one embodiment, the solid pharmaceutical composition includes (1) a first layer which comprises 100 mg Compound 1, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion; and (2) a second layer which comprises 40 mg Compound 2, as well as a pharmaceutically acceptable hydrophilic polymer and a pharmaceutically acceptable surfactant, all of which are formulated in amorphous solid dispersion.
Bibliography:Application Number: SG20201002899V