PROCESSES FOR PREPARING JAK INHIBITORS AND RELATED INTERMEDIATE COMPOUNDS

The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3- d ]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3- d ]pyrimidines are useful as inhibitors of the Janus Kinase family of prote...

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Main Authors XIA, MICHAEL, WANG, HAISHENG, ZHOU, JIACHENG, LIN, QIYAN, LIU, PINGLI, MELONI, DAVID, YUE, TAI-YUEN, RODGERS, JAMES, D, METCALF, BRIAN, W, PAN, YONGCHUN, LI, MEI
Format Patent
LanguageEnglish
Published 28.07.2017
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Summary:The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3- d ]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3- d ]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases.
Bibliography:Application Number: SG2017105183S