MODIFIED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID COMPOSITIONS

The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified n...

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Main Authors ELBASHIR, SAYDA M, AFEYAN, NOUBAR B, SCHRUM, JASON P, VALENCIA, PEDRO, DE FOUGEROLLES, ANTONIN, WOOD, KRISTY M
Format Patent
LanguageEnglish
Published 30.08.2016
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Summary:The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity.
Bibliography:Application Number: SG20161004896T