FORFARANDE FOR FRAMSTELLNING AV C-SUBSTITUERADE PYRIDINER OCH/ELLER HYDRERADE C-SUBSTITUERADE PYRIDINER

• Main Authors: DEUMENS J J M, GROEN S H, JANSSEN P H J, LIPSCH J M J G
• Format: Patent
• Language: Swedish
• Published: 22.11.1976
• Subjects: APPARATUS THEREFOR; CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; CHEMISTRY; GENERAL METHODS OF ORGANIC CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; THEIR RELEVANT APPARATUS; TRANSPORTING

1304155 Pyridines and hydrogenated pyridines STAMICARBON NV 19 April 1971 [8 April 1970] 26131/71 Heading C2C C-Substituted pyridines and/or C-substituted hydrogenated pyridines in which the C-substituents are hydrocarbon groups are prepared by contacting a γ-cyanoketone in the gaseous state and in the presence of hydrogen with a catalyst system which contains silver, copper, gold, iron, cobalt, nickel or a platinum group metal or a compound thereof. Suitable starting cyanoketones are 5-oxohexanenitrile, 5-oxoheptanenitrile, 4-methyl.5-oxohexanenitrile, 2-(#-cyanoethyl) - cyclohexanone, 4 - phenyl - 5 - oxohexanenitrile and 4-methyl-5-oxoheptanenitrile. In the examples, (a) 5-oxohexanenitrile is converted to a mixture of α-pipecoline, α-methyltetrahydropyridine and α - picoline; (b) 4- methyl - 5 - oxohexanenitrile containing some 5-oxoheptanenitrile is converted to 2,3-dimethyl piperidine with small amounts of 2-ethyl piperidine, 2,3-dimethyl pyridine and 2-ethylpyridine; and (c) 2-(#-cyanoethyl)-cyclohexanone is converted to a mixture of quinoline, 5,6,7,8- tetrahydroquinoline and 1,2,3,4 - tetrahydroquinoline.