KRAS G12D INHIBITORS

• Main Authors: Macedonio J. MEJIA, James Gail CHRISTENSEN, Michael Christopher HILTON, Martha E. RODRIGUEZ, James Francis BLAKE, Xiaolun WANG, Pavel SAVECHENKOV, Shelley ALLEN, Mark Joseph CHICARELLI, Brad NEWHOUSE, John GAUDINO, Qian ZHAO, Spencer PAJK, John David LAWSON, Donghua DAI, Tony P. TANG, John Peter FISCHER, Dean Russell KAHN, Aaron Craig BURNS, Guy P. A. VIGERS, Jacob Matthew O'LEARY, Christopher Ronald SMITH, Matthew Arnold MARX, Joshua Ryan DAHLKE, John Michael KETCHAM, Phong NGUYEN, Jay Bradford FELL
• Format: Patent
• Language: Arabic; English
• Published: 28.04.2024
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

يتعلق الاختراع الحالي بمركبات تثبط compounds that inhibit KRas G12D. على وجه التحديد، يتعلق الاختراع الحالي بمركبات تثبط compounds that inhibit نشاط activity KRas G12D، تركيبات صيدلية تشتمل على المركبات compounds وطرق لاستخدامها. The present invention relates to compounds that inhibit KRas G12D. In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.