CARBOXAMIDES, PROCESS FOR PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF

FIELD: medicine. SUBSTANCE: new carboxamides of formula:wherein A, E, G, L, M, R and Q are as defined in the specification and also hydrates or solvates thereof, inhibit thrombin-induced accumulation of throbicides, and coagulation of fibrinogen in blood serum. Said agents can be prepared from the c...

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Bibliographic Details
Main Authors KLAUS GUBERNATOR, KURT KHIL'PERT, ZHAN AKERMANN, DAVID BANNER, ZHERAR SHMID
Format Patent
LanguageEnglish
Russian
Published 20.07.1996
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:FIELD: medicine. SUBSTANCE: new carboxamides of formula:wherein A, E, G, L, M, R and Q are as defined in the specification and also hydrates or solvates thereof, inhibit thrombin-induced accumulation of throbicides, and coagulation of fibrinogen in blood serum. Said agents can be prepared from the corresponding acid and the corresponding amine of formula: HNCHQ.. EFFECT: improved properties of the title compounds. Новые карбоксамиды формулы, приведенной в описании, а также их гидраты или сольваты ингибируют накопление тромбоцитов, индуцированное тромбином, и свертывание фибриногена в плазме крови. Названные вещества можно получать из соответствующей кислоты и соответствующего амина HNCHQ.
Bibliography:Application Number: RU19940032284