CONJUGATE OF A FLUORESCENT DYE WITH A PEPTIDE SUBSTANCE WHICH CONTAINS A PSMA-BINDING LIGAND BASED ON A UREA DERIVATIVE FOR VISUALIZING CELLS EXPRESSING PSMA, A METHOD FOR PRODUCTION THEREOF AND USE THEREOF

• Main Authors: Gorelkin Petr Vladimirovich, Ivanenkov Yan Andreevich, Yamansarov Emil Yulaevich, Machulkin Aleksej Eduardovich, Krasnovskaya Olga Olegovna, Nimenko Ekaterina Alekseevna, Erofeev Aleksandr Sergeevich, Finko Aleksandr Valerevich, Skvortsov Dmitrij Aleksandrovich, Ber Anton Petrovich, Mazhuga Aleksandr Georgievich, Zyk Nikolaj Yurevich, Petrov Stanislav Aleksandrovich, Uspenskaya Anastasiya Alekseevna, Khazanova Elena Sergeevna, Beloglazkina Elena Kimovna
• Format: Patent
• Language: English; Russian
• Published: 04.02.2020
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

FIELD: chemistry.SUBSTANCE: invention refers to organic and medical chemistry, as well as molecular biology and concerns a new class of compounds for visualizing cells and tissues expressing PSMA, including such as prostate cancer cells. Novel diagnostic conjugates are used to visualize pathogenic c...