BENZENESULPHONAMIDE COMPOUNDS APPLICABLE FOR TREATING DISORDERS RESPONSIVE TO DOPAMINE DRECEPTOR MODULATION

• Main Authors: UNGER LILIANE, DRESHER KARLA, TERNER SHON KOL'M, LANGE UDO, BESPALOV ANTON, KHAUPT ANDREAS, JONGEN-RELO ANA LJUSIJA, BRAJE VIL'FRID
• Format: Patent
• Language: English; Russian
• Published: 20.06.2013
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to compounds of formula Iwherein Ris specified in a group consisting of hydrogen and linear C-Calkyl; Rrepresents hydrogen or methyl; Ris specified in a group consisting of hydrogen, C-C-alkyl and C-C-alkoxy, Rrepresents C-C-alkyl; n represents 0, 1 or 2; and physiologically stable salts of these compounds. The invention also refers to a pharmaceutical composition containing at least one compound of formula (I) and possessing dopamine Dreceptor activity and selectivity to the use of the compounds of formula I for treating the disorders responsive to the effect of dopamine Dreceptor antagonists, and further to a method of treating the disorders responsive to the effect of dopamine Dreceptor antagonists and dopamine Dagonists that involves administering an effective amount of at least one compound or a physiologically stable acid addition salt of formula I to an individual in need thereof.EFFECT: there are prepared and described new compounds which can find the application in treating the diseases of the nervous system.27 cl, 18 ex, 1 tbl Изобретение относится к соединениям формулы I