NONAPEPTIDE AMIDE, POSSESSING ABILITY TO PREVENT INCREASE OF VESSEL ENDOTHELIUM PERMEABILITY

FIELD: medicine. ^ SUBSTANCE: invention relates to biologically active peptides, able to prevent sharp increase of permeability of vessel endothelium. Claimed is peptide of formula H-(N-Me)-Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys-NH2 and its pharmaceutically acceptable salts. ^ EFFECT: peptide can be ap...

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Main Authors SEKRIDOVA ALEKSANDRA VLADIMIROVNA, BESPALOVA ZHANNA DMITRIEVNA, KULIKOVA TAT'JANA GAVRIILOVNA, MARCHENKO ALEKSEJ VASIL'EVICH, STEPANOVA OL'GA VLADISLAVNA, SHIRINSKIJ VLADIMIR PAVLOVICH, SIDOROVA MARIJA VLADIMIROVNA, BUSHUEV VALERIJ NIKOLAEVICH, MOLOKOEDOV ALEKSANDR SERGEEVICH
Format Patent
LanguageEnglish
Russian
Published 27.10.2010
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:FIELD: medicine. ^ SUBSTANCE: invention relates to biologically active peptides, able to prevent sharp increase of permeability of vessel endothelium. Claimed is peptide of formula H-(N-Me)-Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys-NH2 and its pharmaceutically acceptable salts. ^ EFFECT: peptide can be applied as anti-edema medication in various fields of medicine. ^ 1 dwg, 2 ex Изобретение относится к биологически активным пептидам, способным предотвращать острое повышение проницаемости сосудистого эндотелия. Предложен пептид формулы H-(N-Me)-Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys-NH2 и его фармацевтически приемлемые соли. Заявленный пептид может найти применение в качестве противоотечного средства в различных областях медицины (в кардиологии, токсикологии, нейрохирургии и др.). 1 ил., 1 табл.
Bibliography:Application Number: RU20090116126