16-{2-BENZOYLAMINO-2-[(3,5-DI-TRET-BUTHYL-4-HYDROXUPHENYL)ALKYL-CARBAMOYL]VINYL}-LABDATRIENS WITH ANTIOXIDANT, HEPATOPROTECTION AND HEMOSTIMULATING EFFECT

FIELD: chemistry. ^ SUBSTANCE: invention concerns new compounds, particularly 16-{2-benzoylamino-2- [(3,5-di-tet-buthyl-4-hydroxyphenyl)-alkylcarbamoyl]vinyl}-labdatriens of the formula (I) with antioxidant, hepatoprotection and hemostimulating effect, allowing for application under toxic hepatitis...

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Main Authors SHUL'TS EHL'VIRA EHDUARDOVNA, SOROKINA IRINA VASIL'EVNA, TOLSTIKOV GENRIKH ALEKSANDROVICH, ZHUKOVA NATAL'JA ANATOL'EVNA, KHARITONOV JURIJ VIKTOROVICH, BAEV DMITRIJ SERGEEVICH, TOLSTIKOVA TAT'JANA GENRIKHOVNA
Format Patent
LanguageEnglish
Russian
Published 20.02.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:FIELD: chemistry. ^ SUBSTANCE: invention concerns new compounds, particularly 16-{2-benzoylamino-2- [(3,5-di-tet-buthyl-4-hydroxyphenyl)-alkylcarbamoyl]vinyl}-labdatriens of the formula (I) with antioxidant, hepatoprotection and hemostimulating effect, allowing for application under toxic hepatitis and in correction of side effects of cytostatic medicines (e.g. cyclophosphane). Compounds of the formula 1 are obtained from raw plant material, Siberian cedar needles or oleo-resin. ^ EFFECT: obtaining compounds with antioxidant, hepatoprotection and hemostimulating effect. ^ 4 tbl, 5 ex
Bibliography:Application Number: RU20070132038