METHOD OF DIAGNOSTICS OF ONCOLOGIC DISEASES IN EXPERIMENT

FIELD: medicine. ^ SUBSTANCE: consistently intravenously enter 1-1000 mcl of 1-10% dextran-ferrofluid in the form of nanoparticles in diameter of 20-900 nanometers in Polyglucinum from calculation of not more than 2.92 mg of Fe/kg of weight of an animal and the magnevist in a dose of 3-12 mcl. Perfo...

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Main Authors PIROGOV JURIJ ANDREEVICH, BRUSENTSOVA TAT'JANA NIKOLAEVNA, KUPRIJANOV DMITRIJ ALEKSEEVICH, DUBINA ANDREJ IVANOVICH, BRUSENTSOV NIKOLAJ ANTONOVICH, SHUMSKIKH MAKSIM NIKOLAEVICH
Format Patent
LanguageEnglish
Russian
Published 20.01.2009
Subjects
DIAGNOSIS
HUMAN NECESSITIES
HYGIENE
IDENTIFICATION
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SURGERY
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Summary:FIELD: medicine. ^ SUBSTANCE: consistently intravenously enter 1-1000 mcl of 1-10% dextran-ferrofluid in the form of nanoparticles in diameter of 20-900 nanometers in Polyglucinum from calculation of not more than 2.92 mg of Fe/kg of weight of an animal and the magnevist in a dose of 3-12 mcl. Perform a magnetic resonance imaging of a body of an animal at T1, T2 weighed gradient-echo sequence. On the basis of results of the visual analysis of the received images diagnose presence of tumours, metastasises and borders of invasion of tumoral cells in healthy tissues. Enter dextran ferrite for 20-40 hours, and magnevist 4-12 minutes prior to carrying out of a magnetic resonance imaging. ^ EFFECT: augmentation of brightness and contrast of images, possibility long time to support contrast of magnitno-resonant image of organs and tissues of animal. ^ 10 ex, 3 tbl, 4 dwg
Bibliography:Application Number: RU20070105144