METHOD FOR POLYMER HYDROGEL PRODUCTION, CONTAINING PHYSIOLOGICALLY ACTIVE SUBSTANCES

FIELD: medicine; pharmacology. ^ SUBSTANCE: method consists in polymer hydrogel production, containing physiologically active substances, by physiologically active substance immobilisation in cross-linked polymer volume, modified with ovomucoid from duck egg-white; the cross-linked polymer being add...

Full description

Saved in:
Bibliographic Details
Main Authors VALUEV IVAN L'VOVICH, SYTOV GENNADIJ ALEKSEEVICH, TALYZENKOV JURIJ AFANAS'EVICH, VALUEV LEV IVANOVICH
Format Patent
LanguageEnglish
Russian
Published 27.12.2008
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

More Information
Summary:FIELD: medicine; pharmacology. ^ SUBSTANCE: method consists in polymer hydrogel production, containing physiologically active substances, by physiologically active substance immobilisation in cross-linked polymer volume, modified with ovomucoid from duck egg-white; the cross-linked polymer being additionally modified with alpha-amylase inhibitor from wheat seed; as physiologically active substance heparin or hirudin is used. The cross-linked polymer modified with ovomucoid and alpha-amylase inhibitor is obtained by chemical modification of polymer with ovomucoid and alpha-amylase inhibitor mix, in proportion of 0.5 to 15 mg ovomucoid to 1 g swollen cross-linked polymer, and 0.5 to 5.0 mg alpha-amylase inhibitor to 1 g swollen cross-linked polymer. ^ EFFECT: hydrogels have anticoagulant activity, are eligible for peroral administration in prevention and treatment for cardiovascular disorders. ^ 2 cl, 20 ex, 1 tbl
Bibliography:Application Number: RU20070127757