APPLICATION OF CYCLIC BIOISOSTER DERIVATIES OF PURINE SYSTEM FOR TREATMENT OF DISORDERS CAUSED BY ABNORMALITIES OF NITRERGIC AND DOPAMINERGIC SYSTEMS

FIELD: medicine; veterinary science. ^ SUBSTANCE: invention refers to application of compounds with common structural formula ^ R1=-H, -NH2, -Br, -Cl, -, -, ^ B=-N=, -CH=, Z=-CH=, -N=, ^ A=-CH- at B=-N=, Z=-CH-, ^ A=-CH- at =-=, Z=-CH=, ^ A=-N= at B=-N=, Z=-CH-, ^ A=-CH- at B=-N=, Z=-N=, ^ A=-CH= at...

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Main Authors POLOSIN VLADIMIR MIKHAJLOVICH, MARKOV ALEKSANDR NIKOLAEVICH, ZHILOV VALERIJ KHAZHMURATOVICH, ZHURAVLEV SERGEJ VLADIMIROVICH
Format Patent
LanguageEnglish
Russian
Published 20.06.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:FIELD: medicine; veterinary science. ^ SUBSTANCE: invention refers to application of compounds with common structural formula ^ R1=-H, -NH2, -Br, -Cl, -, -, ^ B=-N=, -CH=, Z=-CH=, -N=, ^ A=-CH- at B=-N=, Z=-CH-, ^ A=-CH- at =-=, Z=-CH=, ^ A=-N= at B=-N=, Z=-CH-, ^ A=-CH- at B=-N=, Z=-N=, ^ A=-CH= at =-=, Z=-N=. ^ Structures of specified formula are active for nitrergic and dopaminergic systems of mammal body including human body. These compounds can be applied as neuroprotectors, to improve cognitive function and to normalise psychophysiologic state, to treat consequences of substance abuse, as well as to treat wide range of diseases including neuropsychic, cardiovascular, immune, inflammatory and gastro-intestinal disorders. ^ EFFECT: application of new and well-known compound to effect nitrergic and dopaminergic systems for treatment purposes. ^ 4 ex, 3 tbl, 8 dwg
Bibliography:Application Number: RU20060102587