COMBINED THERAPY USING SUBSTITUTED OXAZOLIDINONES

FIELD: organic chemistry, medicine, pharmacology. ^ SUBSTANCE: invention relates to a combination used in prophylaxis and/or treatment of thromboembolic diseases. Combination comprises N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-5-chloro-2-thiophene carboxamide of th...

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Main Authors PERNERSHTORFER DZHOZEF, SHLEMMER KARL-KHAJNTS, LAMPE TOMAS, POL'MANN JENS, PERTSBORN EHLIZABET, RERIG SJUZANNE, SHTRAUB ALEKSANDER
Format Patent
LanguageEnglish
Russian
Published 27.03.2009
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Summary:FIELD: organic chemistry, medicine, pharmacology. ^ SUBSTANCE: invention relates to a combination used in prophylaxis and/or treatment of thromboembolic diseases. Combination comprises N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-1,3-oxazolidin-5-yl}methyl)-5-chloro-2-thiophene carboxamide of the formula (I): its pharmaceutically acceptable salts, hydrates or their mixtures and platelet aggregation inhibitor taken in subtherapeutic effective doses. Also, invention relates to a method for preparing this combination and a drug based on thereof. Proposed combination possesses the enhanced effectiveness. ^ EFFECT: improved and valuable medicinal properties of combination. ^ 4 cl, 2 tbl, 176 ex
Bibliography:Application Number: RU20040101404