N'-{N-[3-OXO-LUPAN-28-OYL]-9-AMINONONANOYL}-3-AMINO-3-PHENYLPROPIONIC ACID AND ITS SALTS AS ANTIVIRAL AND IMMUNOSTIMULATING AGENTS

FIELD: organic chemistry of natural compounds. ^ SUBSTANCE: invention relates to novel compounds, namely, to N'-{N-[3-oxo-lupan-28-oyl]-9-aminononanoyl}-3-amino-3-phenylpropionic acid and its salts of the formula (I) given in the invention description. This compound shows antiviral activity, in...

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Main Authors SHUL'TS EHL'VIRA EHDUARDOVNA, DZHEMILEV USEIN MEMETOVICH, TOLSTIKOV GENRIKH ALEKSANDROVICH, SALAKHUTDINOV NARIMAN FARADOVICH, POKROVSKIJ ANDREJ GEORGIEVICH, TOLSTIKOVA TAT'JANA GENRIKHOVNA
Format Patent
LanguageEnglish
Russian
Published 27.02.2008
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
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Summary:FIELD: organic chemistry of natural compounds. ^ SUBSTANCE: invention relates to novel compounds, namely, to N'-{N-[3-oxo-lupan-28-oyl]-9-aminononanoyl}-3-amino-3-phenylpropionic acid and its salts of the formula (I) given in the invention description. This compound shows antiviral activity, in particular, anti-HIV activity, and immunostimulating activity. Compounds of the formula (I) are nontoxic and can be obtained from betulin isolated from birch bark as available raw with the high yield. ^ EFFECT: valuable medicinal properties of compound. ^ 4 tbl, 9 ex
Bibliography:Application Number: RU20060138356