METHOD FOR TREATMENT OF CHRONIC VIRAL HEPATITIS C OF GENOTYPE-2 WITH MODERATE ACTIVITY

• Main Authors: RADCHENKO VALERIJ GRIGOR'EVICH, CHALISOVA NATAL'JA IOSIFOVNA, KHAAZE GJUNTER, KOMASHNJA ARTEM VLADIMIROVICH
• Format: Patent
• Language: English; Russian
• Published: 20.02.2007
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

FIELD: medicine, hepatology, virology. ^ SUBSTANCE: invention relates to a method for treatment of chronic viral hepatitis C of genotype-2 with moderate activity. Method is carried out by every day parenteral administration of solutions containing a mixture of amino acids, nucleosides and enzyme. In the first day 0.2 ml of 0.01% solution of a solution containing a mixture of amino acids: lysine, arginine, asparagines, glutamic acid taken in the equal amounts is administrated; in the next day 0.2 ml of 0.02% solution containing a mixture of nucleosides: adenosine, inosine, amino acids, guanosine, and enzyme lysozyme also taken in equal amounts. Administration of solution is alternated every day during carrying out the treatment course and each 2 months break in administration of amino acids is carried out for 28-32 days. After 9-11 days of administration of proposed solutions method involves additional course of parenteral administration of interferon-alpha 2b in the dose 3 ml IU, 3 times per a week for 6 months. The total duration of treatment course is 6 months, 9 days - 6 months, 11 days. Method provides clinical remission and elimination of hepatitis virus and normalization of biochemical indices for 6 months after termination of treatment. ^ EFFECT: improved method of treatment. ^ 2 tbl, 4 ex