RECOMBINANT PLASMID DNA pBMC-nef(A)m-1 EXPRESSING PROTEIN NEF OF HUMAN IMMUNODEFICIENCY VIRUS TYPE I VIRUS IN EUCARYOTIC CELLS

FIELD: biotechnology, medicine, molecular biology, genetic engineering, immunology. SUBSTANCE: invention proposes recombinant plasmid DNA pBMC-nef(A)m-1 that comprises gene nef of human immunodeficiency virus type I, subtype A, where in its sequence of nucleotides in codons with prevailing adenine a...

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Bibliographic Details
Main Authors KOZLOV A.P, ROMANOVICH A.EH, MURASHEVA I.V, MURASHEV B.V, MASHARSKIJ A.EH, KLIMOV N.A, POLJAKOVA M.S
Format Patent
LanguageEnglish
Russian
Published 27.05.2004
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:FIELD: biotechnology, medicine, molecular biology, genetic engineering, immunology. SUBSTANCE: invention proposes recombinant plasmid DNA pBMC-nef(A)m-1 that comprises gene nef of human immunodeficiency virus type I, subtype A, where in its sequence of nucleotides in codons with prevailing adenine and/or thymine bases adenine and/or thymine are replaced partially for guanine and/or cytosine. Plasmid provides the expression of protein NEF and can be used for immunization against human immunodeficiency virus. EFFECT: valuable biological and medicinal properties of plasmid DNA. 1 tbl, 3 dwg
Bibliography:Application Number: RU20030116168