METHOD FOR PREPARING SEROTONIN AND ITS PHARMACOLOGICAL SALTS

FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to method for preparing serotonin and its water-soluble pharmacologically acceptable salts. Method involves reduction of 5-benzyloxytryptamine or 5-benzyloxy-3-(2-nitroethyl)-indole in hydrogen flow in the presence of 10% pa...

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Bibliographic Details
Main Authors PANOV A.E, MIKERIN I.E, KRJUKOV L.N, KUZNETSOV S.L, ALFEROV A.V, VORONTSOV E.A, SEVERIN E.S
Format Patent
LanguageEnglish
Russian
Published 20.04.2004
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to method for preparing serotonin and its water-soluble pharmacologically acceptable salts. Method involves reduction of 5-benzyloxytryptamine or 5-benzyloxy-3-(2-nitroethyl)-indole in hydrogen flow in the presence of 10% palladium on activated carbon as a catalyst. Process is carried out under pressure 20-30 atm. Method provides preparing end products with the yield 90-97%. EFFECT: improved preparing method, high yield. 3 cl, 5 sch, 4 ex
Bibliography:Application Number: RU20020128129