1-PHENYL-1-CYCLOPENTYL-4-PIPERIDINO-2-BUTYNE-1-OL HYDROCHLORIDE (PENTIFIN) ELICITING M4 CHOLINE-BLOCKING ACTIVITY

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention proposes a new agent with expressed selective blocking activity with regards to muscarinic receptors of subtype M4 taking part in control over the formation of cAMP and in activation of peptides Gi/Go. Agent represents 1-phenyl-1-cyclopentyl-4...

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Main Authors DAGAEV S.G, KHRABROVA A.V, KOSMACHEV A.B, LIBMAN N.M, KUBARSKAJA L.G, FIL'KO O.A, DOLGO-SABUROV V.B, SOLOV'EVA N.E
Format Patent
LanguageEnglish
Russian
Published 27.02.2004
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:FIELD: organic chemistry, pharmacy. SUBSTANCE: invention proposes a new agent with expressed selective blocking activity with regards to muscarinic receptors of subtype M4 taking part in control over the formation of cAMP and in activation of peptides Gi/Go. Agent represents 1-phenyl-1-cyclopentyl-4-piperidino-2-butyne-1-ol (pentifin) of the formula (I) known early as an agent used in treatment of Parkinson's disease. EFFECT: valuable medicinal properties of agent, expanded assortment of agents of indicated designation. 1 tbl, 1 ex
Bibliography:Application Number: RU20020127885