METHOD OF PREPARING HYPERIMMUNE SERUM AGAINST PIG ERYSIPELAS

biotechnology, veterinary science, immunology. SUBSTANCE: method involves the use of the following antigens: inactivated concentrated cultures of strains Eryipelotrix insidiosa N 1689 of subtype 1a and N 1329 of subtype 1b (serotype A) in the amount 1500-2270 billion cells and living concentrated cu...

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Main Authors SHEIN V.V, KOLOMNINA G.F, GALENSKIJ A.G, SHKOL'NIKOV E.EH, MEN'SHENIN V.V, LUK'JANOVA E.M, SAMUJLENKO A.JA
Format Patent
LanguageEnglish
Published 27.06.2001
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:biotechnology, veterinary science, immunology. SUBSTANCE: method involves the use of the following antigens: inactivated concentrated cultures of strains Eryipelotrix insidiosa N 1689 of subtype 1a and N 1329 of subtype 1b (serotype A) in the amount 1500-2270 billion cells and living concentrated culture of strain N 1933 of subtype 2a (serotype B) in the amount 525-905 billion cells. For development of grund-immunity bullocks are injected subcutaneously in different body parts with inactivated concentrated antigen (serotype A) in the dose 10-15 billion cells and living concentrated antigen (serotype B) in the dose 2-3 billion cells and repeatedly in 21 days in the dose 20-25 billion cells and 5-7 billion cells, respectively. Hyperimmunization is carried out with inactivated concentrated antigen (serotype A) and living concentrated antigen (serotype B) by 8-10-fold with interval for 3-4 days. EFFECT: enhanced activity of end product, decreased process time, simplified process. 2 tbl, 5 ex
Bibliography:Application Number: RU19990103391