METHOD OF PRODUCING TRANSGENIC ANIMAL EXPRESSING HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR IN MAMMARY GLAND AND HYBRID GENE H-GM-1 FOR METHOD REALIZATION

• Main Authors: CHERNYKH V.JA, PROKOF'EV M.I, MEZINA M.N, KOSORUKOV V.S, LAGUTINA I.S, GORODETSKIJ S.I, SHEPEL' N.I
• Format: Patent
• Language: English
• Published: 20.10.2000
• Edition: 7
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BEER; BIOCHEMISTRY; CARE OF BIRDS, FISHES, INSECTS; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; NEW BREEDS OF ANIMALS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; SPIRITS; TRAPPING; VINEGAR; WINE

molecular biology, genetic engineering. SUBSTANCE: human granulocyte colony-stimulating factor is prepared by expression of recombinant proteins in mammary gland of transgenic animals. Milk of transgenic animals is used for preparing human granulocyte colony-stimulating factor. Original genic struct...