AMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION ON SAID

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of amine of the formula (I) where R - halogen atom, hydroxyl, C1-3-alkyl, C1-3-alkoxyl; Q - a residue of the formula (IIa) , (IIb) ; V - methylene or ethylene; X is C0-2-alkylene chain; X' is C1-4-alkylene chain; T...

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Bibliographic Details
Main Authors DEHVID DZHON KHIL, FRANK KERRIGAN, KIT FRANK MARTIN
Format Patent
LanguageEnglish
Published 10.09.1999
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of amine of the formula (I) where R - halogen atom, hydroxyl, C1-3-alkyl, C1-3-alkoxyl; Q - a residue of the formula (IIa) , (IIb) ; V - methylene or ethylene; X is C0-2-alkylene chain; X' is C1-4-alkylene chain; T - phenyl, pyridyl, pyrazinyl, benzo[b]furanyl, 1,4-benzodi-oxanyl, quinazolinyl possibly substituted with halogen atom, methoxyl or trifluoromethyl; m = 0 or 1, and their pharmaceutically acceptable salts which show high affinity to receptors 5-HT1 and D2. EFFECT: high affinity of compounds to receptors. 6 cl, 1 tbl, 28 ex
Bibliography:Application Number: RU19960113203